Syntinate Technology


Products being developed by ORTHOCON® are based on the company’s proprietary Syntinate Technology Platform. The Syntinate Technology Platform incorporates biocompatible and resorbable materials to create synthetic matrices that, when applied to bone, mechanically block bleeding. The HEMASORB® Resorbable Hemostatic Bone Putty is the first commercial product that employs Syntinate Technology.

Highlights of the Syntinate Technology Platform


Resorbable Syntinate products are resorbable via diffusion into surrounding body fluids and normal phagocytosis.

Tunable Solubility Water insoluble components may be incorporated into the Syntinate Technology, allowing tunability of resorption and/or water resistance.

Anhydrous A unique characteristic of the Syntinate system is that water is not necessary for most formulations. Without the presence of water, shelf life stability of a wide variety of products may be maintained for extended periods of time.

Non-Toxic and Broadly Biocompatible Syntinate components are selected from materials that have established safety profiles and whose use in common medical implants is known.

Radiation Sterilizable Most Syntinate compositions can be radiation-sterilized. Additives, depending on their nature, either may be combined with the Syntinate carrier and terminally sterilized in a commercial package, or may be pre-sterilized and then aseptically combined with an appropriate, radiation-sterilized Syntinate carrier.

Stable Syntinate products require no special storage conditions or handling and can be used “off-the-shelf.”






ORTHOCON® estimates that over 3.5 million patients undergoing surgeries in the United States and Europe each year could benefit from the intraoperative use of HEMASORB.


Canaan Partners Closes $600 Million Fund, Canaan IX
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ORTHOCON® Announces Signing of Exclusive, Worldwide License Agreement with Bezwada Biomedical
August 31, 2011 - Click to Download